CML File

What are CML files and how to open them

Are you having problems opening a CML file or just wondering what they contain? We explain what these files are used for and show you software that we know can open or otherwise handle your files.

What is a CML file?

CML files have multiple uses, and Chemical Markup Language Document is one of them. Read more about the other uses further down the page.

Chemical Markup Language Document

These CML files contain chemical information used by chemists. The data stored includes molecules, reactions, analytical data, and chemical materials. It is used for information management about specific chemicals.

How to open CML files

We have identified one CML opener that is compatible with this specific type of CML file.

Programs that open Chemical Markup Language Document files


Last updated: December 10, 2022

More file formats using the CML extension

Through our research of CML files, we know that the following formats exist. However, we have not yet analyzed them in detail.

  • ChordML Music Document
  • UniComal COMAL 80 Library

Various apps that use files with this extension

These apps are known to open certain types of CML files. Remember, different programs may use CML files for different purposes, so you may need to try out a few of them to be able to open your specific file.

Infrared Library ManagerInfrared Library ManagerUser submitted
ChemAxon MarvinChemAxon MarvinUser submitted
SIGRASIGRAUser submitted
Sasi50_v0Sasi50_v0User submitted
CimCAD / CimPackCimCAD / CimPackUser submitted
PulsonixPulsonixUser submitted
ChemAxon Marvin SuiteChemAxon Marvin SuiteUser submitted

Help us help others helps thousands of users every day, and we would love to hear from you if you have additional information about CML file formats, example files, or compatible programs. Please use the links below or email us at to discuss further.